CAS #: 90045-36-6
HS code: 13021940.00
In the 1960s, the Dr. Willmar Schwabe Group developed a standardized Ginkgo biloba extract known as EGb 761, which is recognized for promoting vasodilation and enhancing blood flow. This extract is used to treat various conditions, including memory loss and tinnitus[1].
In 2014, an assessment report by the European Medicines Agency (EMA) acknowledged the therapeutic benefits of Ginkgo biloba extract in improving age-related cognitive impairment and enhancing the quality of life in individuals with mild dementia[2].
In the United States, Ginkgo biloba extract is also widely used as a dietary supplement[3].
In China, Ginkgo biloba extract preparations are primarily used for:
Enhancing blood circulation and relieving collateral obstruction. This includes treatment for conditions such as chest congestion, angina, stroke, hemiplegia, stiff tongue caused by blood stasis, and collateral blockage, as well as stable angina pectoris and cerebral infarction associated with these syndromes[4].
Delekang’s Ginkgo biloba extract has been approved by the State Administration for Market Regulation (formerly the China Food and Drug Administration) for use as an Active Pharmaceutical Ingredient (API) in the production of various drug formulations. Additionally, we have obtained a Food Production License, authorizing the manufacture of Ginkgo biloba extract for use in dietary supplements.
Ginkgo biloba extract is a widely used ingredient, produced by many plant extract manufacturers. However, consistently achieving high — let alone excellent — quality is a challenge that only a few can meet. Over the past decade, we have continuously enhanced the quality of our Ginkgo biloba extract through the following measures:
Stable Raw Material Supply: We maintain long-term partnerships with ginkgo leaf suppliers, enabling us to collect and analyze extensive quality data from different regions. This ensures the selection of optimal raw materials for standardized products with consistent quality.
Compliance with Pharmacopoeial Standards: Our production process strictly follows the requirements of the Chinese Pharmacopoeia, U.S. Pharmacopoeia, and European Pharmacopoeia.
Regulatory Compliance: We fully comply with EU regulations on maximum pesticide residue levels (EC No 396/2005).
Strict Safety Standards: Our extract contains ginkgolic acid at levels below 1 ppm and ginkgotoxin below 50 ppm.
Certified Production Facilities: Our production line is registered with the State Administration for Market Regulation and certified with a Certificate of Suitability (CEP) by the European Directorate for the Quality of Medicines (EDQM).
Versatile Formulation: Our extract is compatible with most oral dosage forms, making it suitable for a wide range of pharmaceutical applications.
In addition to maintaining high quality, Delekang is committed to offering cost-effective solutions. As a specialized manufacturer, we have the following competitive advantages:
Efficient Use of Resources: Our advanced technology enables the comprehensive utilization of raw materials, reducing production costs. Extracted ginkgo leaves and by-products are further processed to obtain sodium copper chlorophyllin and shikimic acid. Spent leaves are repurposed as biomass fuel, supplying renewable energy to our production line.
Economies of Scale: Our large-scale operations allow us to spread fixed costs — including R&D, equipment, and infrastructure — across a greater volume of output, resulting in more competitive pricing.
Specialized Production Line: Unlike generic extraction equipment, our purpose-built production line for Ginkgo biloba ensures better quality control and greater cost efficiency.
| Item | CP | USP | EP | In-house |
|---|---|---|---|---|
| Flavonol glycosides | ≥24.0% | 22.0-27.0% | 22.0-27.0% | 22.0-27.0% |
| Terpene lactones | ≥6.0% | 5.4-12.0% | 5.4-6.6% | 5.4-12.0% |
| Bilobalide | / | 2.6-5.8% | 2.6-3.2% | 2.6-5.8% |
| Ginkgolide | / | 2.8-6.2% | 2.8-3.4% | 2.8-6.2% |
| Quercetin/kaempferol ratio | 0.8-1.2 | / | / | 0.8-1.2 |
| Isorhamnetin/Quercetin ratio | ≥0.15 | / | / | ≥0.15 |
| Ginkgolic acid | ≤5mg/kg | ≤5mg/kg | ≤5mg/ kg | ≤1mg/kg |
| Free quercetin | ≤10mg/g | ≤5mg/g | / | ≤10mg/g |
| Free kaempferol | ≤10mg/g | / | / | ≤10mg/g |
| Free isorhamnetin | ≤4mg/g | / | / | ≤4mg/g |
| Rutin | / | ≤4.0% | / | / |
| Pesticide residues | / | USP<561> | EC396/2005 | / |
| Loss on drying | ≤5.0% | ≤5.0% | ≤5.0% | ≤4.0% |
| Residue on ignition | ≤0.8% | / | / | ≤0.8% |
| Heavy metals | ≤20m g/kg | / | / | ≤15m g/kg |
| HPLC Fingerprint | ≥0.90 | / | / | ≥0.90 |
25 kg/drums
Store in light-tight, airtight and dry condition